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Current Deficiencies in The Rational Development of CBD-based Wellness Products
May 5, 2021

Current Deficiencies in The Rational Development of CBD-based Wellness Products

  • Even major players in the CBD market do not offer detailed and verifiable study results to effectively differentiate their products on the basis of meaningful clinical findings, essentially exploiting the “natural” label without any R&D efforts
  • This industry deficiency represents immense opportunities for R&D-driven companies such as Green Hygienics
  • Green Hygienics intends to use its intellectual and capital resources to establish and apply state-of-the-art research and development to a new generation of cannabinoid-based products having specifically assessed health-wellness efficacies

CBD Reality Check 

Interest in the therapeutic use of hemp-derived nonintoxicating cannabinoids, such as cannabidiol (“CBD”) and cannabigerol (“CBG”), has reached a fever-pitch in recent years followed by the early-stage preclinical discoveries surrounding the tentative functional role of the endocannabinoid system (“ECS”). CBD received a further popular validation since U.S. FDA approved Epidiolex(R) as adjunctive therapy for pediatric patients with drug-resistant epilepsy. 

During the last 5-8 years, CBD has been highly acclaimed and heavily hyped. Its medicinal qualities are perceived as limitless by some, and its non-psychoactive nature makes it “suitable” for just about anyone, as it has been claimed by many activists and business entities. The broad-ranging claims of CBD therapeutic utilities are endless, while monopolistic entrepreneurs are rushing the industry in droves, touting first-to-market achievements over quality, research-backed product offerings. 

Current Status-Quo and Future Expectations 

A case can be made that the majority of CBD companies simply ignore the lack of efficacy in their products to avoid potentially undermining their commercial utility, preferring to exploit the “natural” label without any R&D efforts, the very efforts that could establish important evidence-based credibility for their products. Companies marketing products containing CBD have been over-exuberant in their claims about its effectiveness. They have been guilty of illegal, sleight-of-hand, exploiting public enthusiasm over cannabis/hemp by portraying all cannabinoids as not only safe but capable of ameliorating the symptoms of many serious medical conditions.

Consequently, the reputation of CBD as a universal “cure-all” puts this still promising substance in the same class as other “natural” panaceas, where anecdotal cases and overwhelmingly biased testimonials supersede the proper efficacy evaluation of already marketed CBD finished products.

Notwithstanding, while CBD and other hemp-derived cannabinoids remain a formally unproven therapeutic option with a known mechanism of action, physicians and holistic health/wellness practitioners remain open to the possible future role of these products in the field of alternative management and prophylaxis of different health conditions such as chronic inflammation and pain. Emerging companies like Green Hygienics Holdings (OTCQB: GRYN) have an opportunity to paint a brighter future for the CBD industry and provide a research-based platform for which these physicians and holistic health/wellness practitioners can specifically select and recommend beneficial products meaningful to their intended purpose of providing patient relief.  

To recommend a particular cannabinoid-based product to patients and wellness-oriented end-users, those practitioners need to adequately analyze specific information and study reports on the experimentally assessed systemic exposure, bioavailability and targeted efficacy of a particular product, instead of focusing solely on the certificate of analysis (“COA”) that verifies only the concentration of bio-active ingredients and absence of harmful contaminants. 

A very brief survey gathered from the published scientific and commercial papers or conference presentations indicates that even the major players in the CBD market do not possess such study results and reports to differentiate and promote their products based on at least preclinical and/or exploratory clinical study findings. 

Green Hygienics is Poised to Address the Current State of the Industry

On the other hand, this particular status-quo represents the immense opportunities for R&D-driven companies like Green Hygienics in an everchanging cannabinoid market landscape. Physicians and holistic health/wellness practitioners are looking for more advanced, evidence-based cannabinoid products with high, unparalleled, and most importantly unbiased therapeutic efficacies of achievable health-beneficial effects. Green Hygienics is an enterprise that has developed a model resting on this exact premise of bringing evidence-based cannabinoid products to market, backed with unbiased therapeutic efficacies, through research-based evidence.

The company aims to be a leader in compliance and capabilities in the hemp and cannabinoid supply marketplace. By leveraging state of the art technologies, the company intends to open up a whole new world of fully characterized novel cannabinoids and targeted bio-delivery technologies never before explored.

Green Hygienics is aimed at maximizing the use of intellectual and capital resources. Therefore, the Company has decided to move forward with the establishment of a state-of-art biotechnology R&D facility to focus its resources on the rational and innovative design of formulations, development and experimental evaluation of the new generation cannabinoid-based products with superior bioavailability and specifically assessed health-wellness efficacies.

Discovery and development of highly efficacious cannabinoid-based products is a global task that is based on multidisciplinary approaches, collaborations, and partnerships. Therefore, Green Hygienics is building its collaborative platform with several academic institutions, both domestically and abroad, to utilize well established endocannabinoid system (“ECS”) target screening models and develop customized wellness products addressing ECS deficiencies. The ultimate goal is to develop and promote highly functional, experimentally assessed and supported efficacious nutraceutical products that will be trusted by medical communities, physicians, holistic health practitioners, and wellness-oriented end users. 

For a more in-depth exploration on this topic, please refer to this paper published in Nutritional Outlook by Levan Darjania, PhD. (  

About Green Hygienics Holdings

Green Hygienics Holdings Inc. (OTCQB: GRYN) is a California-based innovative, technology-driven enterprise focused on the high standard cultivation and processing of industrial hemp and manufacturing of pharmaceutical-grade bioactive cannabinoids.

The company’s corporate mission is to adhere to the highest standards of operations in consistently delivering safe and premium-quality products to consumers as well as to partner with CPG (consumer packaged goods) and pharmaceutical companies.

The company intends to be a leader in compliances and capabilities in the hemp and cannabinoid supply marketplace. Using state-of-the-art technologies, Green Hygienics intends to open a whole new world of novel cannabinoids and targeted bio-delivery technologies never before explored, solving the issues of stability, pharmacokinetics, biological tissue penetration and bioavailability.

GRYN is building a team of visionary agrotechnology, pharmaceutical and life scientists working at the intersection of nutraceutical, cosmeceutical and pharmaceutical technologies with a goal to improve lives.

View GRYN’s corporate video and follow the company on Facebook, Twitter and Linkedin.

Corporate Communications:
Heidi Thomasen
[email protected]
Toll Free 1.855.802.0299

For more information, visit the company’s website at

NOTE TO INVESTORS: The latest news and updates relating to GRYN are available in the company’s newsroom at

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