Telomir Pharmaceuticals (NASDAQ: TELO), an emerging leader in age-reversal science, announced significant findings from a preclinical progeria lifespan study in collaboration with Nagi Bioscience SA. Using C. elegans nematode models with wrn-1 gene mutations (analogous to human Werner Syndrome), the study demonstrated that Telomir-1 restored lifespan and normalized aging effects, including improved movement velocity and tail amplitude. Telomir-1 targets cellular dysfunction by regulating metal imbalances, reducing oxidative stress, and addressing telomere shortening, offering therapeutic promise for conditions like progeria and age-related diseases. Telomir plans to advance research with in vitro studies on human progeria cell lines.
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About Telomir Pharmaceuticals
Telomir Pharmaceuticals is a preclinical stage pharmaceutical company seeking to lead development in longevity science in both humans and animals. The company is focused on the development of Telomir-1, a novel small molecule designed to lengthen the DNA’s protective telomere caps, which are crucial in the aging process. Telomeres are the protective end caps of a chromosome made up of DNA sequences and proteins. As humans age, telomeres shorten, with metal reactivity accelerating the process, which presents humans and pet animals with an increased chance of contracting a number of degenerative and age-related diseases. Telomir’s goal is to develop, gain regulatory approval for and commercialize Telomir-1, proposed to be dosed orally, with the broader aim of promoting longevity and enhancing overall quality of life. For more information about the company, visit the website www.Telodx.com.
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