Telomir Pharmaceuticals (NASDAQ: TELO), a preclinical-stage biotechnology company developing small-molecule therapeutics targeting epigenetic and metabolic drivers of disease, announced positive results from a completed efficacy study evaluating Telomir-1 (Zn-Telomir) in zebrafish tumor xenograft models of triple-negative breast cancer conducted in collaboration with BioReperia using its ZTX(R) ONCOLEADS platform. In an aggressive TNBC model with limited responsiveness to paclitaxel, Telomir-1 demonstrated statistically significant reductions in primary tumor growth and metastatic dissemination, while in a separate aggressive TNBC model where paclitaxel showed activity, Telomir-1 achieved comparable tumor growth reduction as a monotherapy and produced greater inhibition when combined with paclitaxel than either agent alone.
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About Telomir Pharmaceuticals
Telomir Pharmaceuticals (NASDAQ: TELO) is a preclinical biotechnology company developing small-molecule therapeutics designed to target the root epigenetic mechanisms underlying cancer, aging, and degenerative disease. The Company’s lead candidate, Telomir-1, has demonstrated activity in preclinical studies involving modulation of DNA and histone methylation, restoration of redox balance, and normalization of cellular function.
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