Kairos Pharma (NYSE American: KAPA) announced the inclusion of City of Hope Cancer Center in California in its Phase 2 clinical trial for ENV105, targeting castrate-resistant prostate cancer. The trial, supported by Kairos Pharma and a National Cancer Institute grant, evaluates ENV105’s potential to overcome hormone therapy resistance in combination with apalutamide. Adding City of Hope allows for a broader patient population and the identification of biomarkers to optimize treatment. Kairos executives highlighted the strong preclinical evidence and collaboration with City of Hope’s expert oncologists as pivotal steps in developing innovative therapies for patients resistant to standard hormone treatments.
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About Kairos Pharma Ltd.
Based in Los Angeles, California, Kairos Pharma is at the forefront of oncology therapeutics, utilizing structural biology to overcome drug resistance and immune suppression in cancer. Its lead candidate, ENV105, is an antibody that targets CD105—a protein identified as a key driver of resistance to various cancer treatments. Elevation of CD105 in response to standard therapy results in resistance and disease relapse. ENV105 aims to reverse drug resistance by targeting CD105 and restore the effectiveness of standard therapies across multiple cancer types. Currently, ENV105 is in a Phase 2 clinical trial for castrate resistant prostate cancer and a Phase 1 trial for lung cancer, addressing significant unmet medical needs. For more information, visit the company’s website at www.KairosPharma.com.
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